Incidence and major clinical approaches of aneurismatic bone cysts: a concise systematic review

Introduction: Aneurysmal bone cysts (ABC) are pseudocysts expansive lesions. The World Health Organization (WHO) categorizes primary ABCs as cystic neoplasms that contain fibrous septa separating numerous blood-filled spaces. Approximately 70% of ABC cases primary, while 30% secondary. Objective: present study aimed to carry out a concise systematic review the main clinical findings aneurysmal cysts, highlighting incidence and prevalence, well forms treatment. Methods: rules Systematic Review-PRISMA Platform were followed. research was carried from May 2022 July developed based on Scopus, PubMed, Science Direct, Scielo, Google Scholar. quality studies GRADE instrument risk bias analyzed according Cochrane instrument. Results: A total 143 articles found. In total, 73 evaluated 10 included in review. symmetric funnel plot does not suggest bias. After prospecting literary findings, it generally evidenced cyst is rare lesion more frequently found young adults children. It may have unpredictable behavior, with high recurrence rate after Standard treatment consists curettage plus local adjuvants grafting fill void. anatomic sites difficult surgical access, percutaneous procedures used (injection sclerosing agents, radiofrequency thermal ablation, or selective arterial embolization. Medical management bisphosphonates denosumab has also been advocated. Conclusion: Primary involving maxillofacial region extremely even patients advanced age. Next-generation sequencing confirmed presence USP6-CDH11 fusion gene, consistent classification cyst. Sclerotherapy provided an effective minimally invasive for particularly useful deep injuries, challenging potentially injurious vital structures.